🎓 Prepared by students from Boğaziçi University

What is Digestion and How Do Digestive Enzymes Work?

Digestion is the process of breaking down food into smaller molecules the body can absorb and use for energy. Digestive enzymes are biological catalysts that speed up this breakdown, each targeting a specific type of nutrient — carbohydrates, proteins, or fats. Together, mechanical and chemical digestion turn a meal into usable building blocks for the body.

Short answer

Digestion breaks food into absorbable nutrients using digestive enzymes such as amylase (carbohydrates), pepsin (proteins), and lipase (fats), each working best in a specific part of the digestive tract.

The Path of Digestion
  1. 1
    Mouth
    Chewing plus salivary amylase begins breaking down starch
  2. 2
    Stomach
    Pepsin and stomach acid break down proteins
  3. 3
    Small Intestine
    Pancreatic amylase, lipase and trypsin digest carbs, fats and proteins
  4. 4
    Absorption
    Nutrient molecules pass through the intestinal wall into the bloodstream
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Step-by-step worked examples

A slice of bread contains starch. Which enzyme starts breaking it down, and where?

Starch is a carbohydrate
Salivary amylase begins breaking it into smaller sugars in the mouth

A piece of chicken (protein) is eaten. Which enzyme breaks it down, and where?

Protein digestion starts in the stomach
Pepsin, activated by stomach acid (HCl), breaks proteins into smaller peptides

A meal contains 60 g of fat. Which enzyme digests it, and what does it produce?

Fats are digested mainly in the small intestine
Lipase (helped by bile) breaks fat into fatty acids and glycerol for absorption
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Flashcards

03

Quick quiz

Q1.Which enzyme breaks down starch?

Correct answer: B. Amylase, found in saliva and pancreatic juice, breaks starch into sugars.

Q2.Where does protein digestion mainly begin?

Correct answer: B. Pepsin in the stomach starts breaking proteins into peptides.

Q3.What does lipase break fats into?

Correct answer: C. Lipase splits fats into fatty acids and glycerol for absorption.

Q4.What helps activate pepsin in the stomach?

Correct answer: B. Hydrochloric acid converts pepsinogen into active pepsin.
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Common mistakes

Thinking all digestion happens in the stomach.Correct: Digestion starts in the mouth and is completed mostly in the small intestine.

Confusing bile with an enzyme.Correct: Bile is not an enzyme — it emulsifies fat so lipase can work more effectively.

Believing amylase digests protein.Correct: Amylase digests carbohydrates/starch, not protein.

Assuming absorption happens in the stomach.Correct: Most nutrient absorption happens in the small intestine, not the stomach.

05

FAQ

What are digestive enzymes?

Proteins that speed up the breakdown of food into absorbable nutrients, such as amylase, pepsin and lipase.

How does digestion work step by step?

Food is broken down mechanically and chemically from the mouth through the stomach to the small intestine, where nutrients are absorbed.

What are examples of digestive enzymes?

Amylase (carbs), pepsin (protein), lipase (fats) and trypsin (protein) are common examples.

How is digestion different from absorption?

Digestion breaks food down into smaller molecules; absorption is when those molecules pass into the bloodstream.

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